In August 2021, a suspected case of Ebola was identified at a hospital in Abidjan, Côte d’Ivoire. The patient had recently travelled from Labé, Guinea to Abidjan by road and was admitted to a hospital after experiencing a fever.1 If confirmed, this will be the first case of Ebola in Côte d’Ivoire since 19942,3 and is of additional concern due to the ongoing COVID-19 pandemic4 and high regional and cross-border movement. This brief draws on the technical paper for the Tackling Deadly Diseases in Africa (TDDA) programme (July 2021), to present key social science considerations for epidemic response and preparedness in Côte d’Ivoire, with relevance to the current situation. This updated summary includes new material from a rapid literature review and consultations with social science and public health experts in-country.